The present invention addresses the problem of providing a novel formulation for which constraints on patient administration have been relaxed compared to previous spherical carbon adsorbents, allowing said formulation to be administered simultaneously with other agents and at a reduced dose. This problem can be solved with an orally administered formulation that includes a porous material, wherein the porous material is provided with a means for first exposing the surface of the porous material in the large intestine or the lower small intestine.