MAP2K1 (MEK1) AS A THERAPEUTIC TARGET FOR ARTERIOVENOUS MALFORMATIONS AND ASSOCIATED DISORDERS

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专利权人:

Children's Medical Center Corporation

发明人:

Arin K. Greene,Matthew Warman,Yue Huang

申请号：

US16474976

公开号：

US20200024666A1

申请日:

2017.12.29

申请国别(地区):

US

年份:

2020

代理人:

摘要：

Please insert the following Abstract on a separate sheet at the end of the application: The instant disclosure provides methods and compositions related to discovery of MAP2K (MEK1) as a therapeutic target for treatment or prevention of arteriovenous malformations (AVMs). Therapeutic and/or prophylactic uses and compositions of known MEK1 inhibitors, including small molecules and nucleic acid agents, are described.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/