Aaron K. Sato,Daniel J. Sexton,Daniel T. Dransfield,Robert Charles Ladner
申请号：
US14019241
公开号：
US09629934B2
申请日:
2013.09.05
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention provides polypeptides, peptide dimer, and multimeric complexes comprising at least one binding moiety for KDR or VEGF/KDR complex, which have a variety of uses wherever treating, detecting, isolating or localizing angiogenesis is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding KDR or VEGF/KDR complex with high affinity (e.g., having a KD<；1 μM), and dimer and multimeric constructs comprising these polypeptides.
