Chimeric polynucleotide and polypeptide that allows the secretion of the binding to the polypeptide of interest in exosomes, as well as their use in the production of an immunogenic composition
The present invention also concerns exploiting the properties of exosomes comprising a polypeptide of the invention and of immunogenic compositions of the invention for the prophylaxis and/or treatment of an infection by a pathogenic agent, a pathogenic organism, a tumour antigen or a cytoplasmic antigen, in particular to elicit or promote, in vivo, in a host, in particular in a human or non-human mammal or a bird, a humoral and/or cellular response against a virus, bacterium, parasite or tumour.