A compound prescription colloidal eyedrop gel is provided. The compound prescription colloidal eyedrop gel includes a plurality of carboxymethyl-hexanoyl chitosan (CHC) micelles, a basic structural stabilizer connecting the plurality of CHC micelles, a plurality of first drugs inside the plurality of CHC micelles, and a plurality of second drugs outside the plurality of CHC micelles.本發明提供一種滴點式複合藥物凝膠,包含複數個幾丁聚醣微胞、鹼性結構安定劑以連接複數個幾丁聚醣微胞、第一藥物於複數個幾丁聚醣微胞之內、以及第二藥物於複數個幾丁聚醣微胞之外。10‧‧‧滴點式複合藥物凝膠110‧‧‧幾丁聚醣微胞111‧‧‧親水端112‧‧‧親油端120‧‧‧鹼性結構安定劑130‧‧‧第一藥物140‧‧‧第二藥物150‧‧‧保存劑