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Selective hydroxamic acid based MMP-12 and MMP-13 inhibitors
专利权人:
Sven Weiler;Leslie Wighton McQuire;Ruben Alberto Tommasi;Michael Shultz
发明人:
Leslie Wighton McQuire,Olivier Rogel,Michael Shultz,Ruben Alberto Tommasi,Sven Weiler
申请号:
US14042652
公开号:
US08841291B2
申请日:
2013.09.30
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides a compound of formula (I):said compound is inhibitor of MMP-12 and/or MMP-13, and thus can be employed for the treatment of a disorder or disease characterized by abnormal activity of MMP-12 and/or MMP-13. Accordingly, the compound of formula (I) can be used in treatment of disorders or diseases mediated by MMP-12 and/or MMP-13. Finally, the present invention also provides pharmaceutical composition that include the compound of formula (I).
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