Various aspects of a system and method to process an image for generation of a three-dimensional (3D) view of an anatomical portion are disclosed herein. The system includes an image-processing device configured to receive a plurality of two-dimensional (2D) images associated of an anatomical portion, each with a first field-of-view (FOV) value. A first 3D view of the anatomical portion with a second FOV value, is generated from a 3D reconstruction of the anatomical portion. The 3D reconstruction is obtained by use of a set of 2D image frames selected from the received plurality of 2D images. The second FOV value is greater than the first FOV value of each of the plurality of 2D images of the anatomical portion. A second 3D view is generated, based on the alignment of the generated first 3D view with 3D data associated with a pre-operative state of the anatomical portion.
