BOICE, MICHAEL HENRY,WENDEL, HANS GUIDO,SALLOUM, DARIN
申请号:
CA2981304
公开号:
CA2981304A1
申请日:
2016.04.04
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
In some aspects the present invention provides methods for the treatment of B-cell lymphomas. Some such methods involve administration of HVEM ectodomain polypeptides, anti-HVEM antibodies, or anti-BTLA antibodies to subjects in need thereof. Some such methods involve use of CAR T cells, such as CD19-specific CAR T cells. The present invention also provides compositions useful in such methods. These and other embodiments of the present invention and described further herein.