Frank F. Molock, Jr.;Annabelle Gallois-Bernos;Kathrine Osborn Lorenz;Carrie L. Davis;James K. Young;Kristy L. Canavan;Fang Lu
发明人:
Annabelle Gallois-Bernos,Frank F. Molock, Jr.,Carrie L. Davis,Kathrine Osborn Lorenz,James K. Young,Kristy L. Canavan,Fang Lu
申请号：
US13495049
公开号：
US10383839B2
申请日:
2012.06.13
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to ophthalmic compositions and methods for the treatment of dry eye and other inflammatory ocular conditions. In particular, the present invention relates to a composition comprising an esterified anti-inflammatory lipid mediator, which is an ester of an anti-inflammatory lipid mediator that is a reaction product of the anti-inflammatory lipid mediator and a monohydric alcohol or an amide wherein the majority of the anti-inflammatory lipid mediator is present in an ester form. In this way, the compositions are substantially free of an acid form of the anti-inflammatory lipid mediators. This composition can be topically delivered to the ocular surface via a preparation, solution, gel, ointment, and/or strip and/or a contact lens.
