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Methods of increasing muscle mass using follistatin-like related gene (FLRG)
专利权人:
Se-Jin Lee
发明人:
Se-Jin Lee
申请号:
US12529179
公开号:
US08236751B2
申请日:
2008.03.06
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present relates to use of follistatin-like related gene (FLRG) to increase muscle mass in a subject. As such, methods of ameliorating the severity of a pathologic condition characterized, at least in part, by a decreased amount, development or metabolic activity of muscle are provided. In addition transgenic non-human mammals expressing FLRG and having increased muscle mass as compared to a corresponding mammal having a myostatin-null mutation or a decreased level of myostatin are provided.
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