Provided are an endoscope and a method of manufacturing an endoscope capable of positioning an imaging element and a lens assembly with high accuracy, forming an optical image with high accuracy on an image reception surface of the imaging element to obtain a high-quality image with little loss of to image, defocusing, and the like, performing easy assembling, and firmly joining members.The endoscope has an imaging element； a lens assembly that forms an optical image on an image reception surface of an imaging element； a cable that is connected to a connecting terminal provided on a surface opposite to the image reception surface of the imaging element； a case that protects a joined part between the connecting terminal of the imaging element and the cable； and a holder that holds the lens assembly and is joined to the case. The case has an opening part penetrating in an arrangement direction of the imaging element and the cable, and is disposed such that an opening surface on the imaging element side is in contact with an end surface of the holder. The imaging element is disposed such that the imaging element abuts against at least one of inner wall surfaces of the opening part of the case in a lateral surface and the image reception surface abuts against the end surface of the holder.
