Anti-TLR4 Antibodies and Methods of Use Thereof

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专利权人:

Novlmmune S.A.

发明人:

Emmanuel Monnet,Limin Shang,Susana Salgado-Pires,Walter Ferlin,Greg Elson

申请号：

US14563112

公开号：

US20150158946A1

申请日:

2014.12.08

申请国别(地区):

US

年份:

2015

代理人:

摘要：

This invention relates generally to anti-Toll-like Receptor 4 (TLR4 antagonists) including antibodies that specifically bind Toll-like Receptor 4 (TLR-4), to methods of using the anti-TLR4 antagonists as therapeutics and to methods of using the anti-TLR4 antagonists for inhibiting, delaying the progression of, or otherwise ameliorating a symptom of Graft-versus-Host disease (GvHD) and/or improving survival of GvHD subjects and/or transplanted biological materials in subjects.

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