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KILLER CELL CAPABLE OF EFFICIENTLY AND STABLY EXPRESSING ANTIBODY, AND USES THEREOF
专利权人:
Shanghai Cell Therapy Group Co., Ltd.;Shanghai Cell Therapy Research Institute
发明人:
Qijun QIAN,Huajun JIN,Jieying XU,Linfang LI,Zhenlong YE,Zhou HE,Lianzhen CUI,Hongping WU
申请号:
US16311084
公开号:
US20200289561A1
申请日:
2017.06.19
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided is a transgenic killer cell, the genome of which is stably integrated with a coding sequence comprising an antibody of a human Fc section, or an expression cassette of a coding sequence comprising a chimeric antigen receptor or an inhibitory or agonistic antibody, and an inverted terminal repeat sequence from a transposon at both ends. Also provided is a pharmaceutical composition comprising the transgenic killer cell, and uses thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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