This work reveals an active bone filling material with growth promoting nuclear structure.There is a core main structure.A growth promoting activation layer coated on the surface of the main structure of the nucleus;And a plurality of microporous structures arranged on the main structure of the core;The micropore structure is dispersed in the growth promoting activation layer and forms a holding space connected with each other.A plurality of first growth promoting activation chains, a plurality of second growth promoting activation chains and a plurality of growth promoting activation points are arranged in the accommodation space.本創作揭示一種用於重建修復具有生長促進核結構之活性骨填補物,其中包含有一核主體結構;一包覆於該核主體結構表面的生長促進活化層;以及複數個設置於核主體結構上的微孔洞結構;其中該微孔洞結構分散設置於該生長促進活化層並形成彼此相互通連的一容置空間,在該容置空間內分散設置有複數個第一生長促進活化鏈與複數個第二生長促進活化鏈以及複數個生長促進活化點。