A cartridge with injection needles for an injection device. The cartridge includes a plurality of injection needle assemblies, each including a hub and a needle having ends that face in a first direction. The cartridge also includes a needle assembly support defining a plurality of needle assembly accommodating cavities in which the injection needle assemblies are mounted to be shiftable in the first direction from a retracted position to an injection position, during which shifting a second hub portion moves relative to a first hub portion between a ready arrangement and a needle assembly lifting arrangement. The needle assembly support is loadable into the injection device to be movable therein to allow for separate operational alignment of each injection needle assembly with the drive member (320) of the injection device. The cartridge includes a hub having drive member engageable push and pull surface.