The present invention relates to a short peptide as therapeutic agent and a medicinal composition including the same for inhibiting activities of cancer cells, which includes at least one short peptide listed as SEQ ID NOs: 1 and 2, either of which has no more than 40 amino acid residues, thereby specifically inhibiting activities of cancer cells such as the cell proliferation, cancer stemness, cell migration, cancer cell invasion, metastasis or drug resistance.本發明有關於一種短肽治療劑及含此之醫藥組成物,其中短肽治療劑包括如SEQ ID NO:1及SEQ ID NO:2所示之胺基酸序列之至少一短肽,且此短肽之任一者包括不超過40個胺基酸殘基,以抑制癌細胞之增生、癌幹原細胞性、移行、侵襲、轉移或抗藥性等活動。
