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Cell-free tissue replacement for tissue engineering
专利权人:
发明人:
Christine E. Schmidt,Terry Hudson
申请号:
US14274156
公开号:
US09597429B2
申请日:
2014.05.09
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention is a natural, cell-free tissue replacement that does not require difficult or extensive preparation made by washing tissue replacement in a solution including one or more sulfobetaines and an anionic surface-active detergent and washing the tissue replacement in serial solutions of the buffered salt to remove excess detergent. The natural, cell-free tissue replacement may be a nerve graft that supports axonal regeneration, guides the axons toward the distal nerve end and/or is immunologically tolerated. Other forms of the invention are a composition and kit prepared by the method of making a native, cell-free tissue replacement. The present invention may be modified for use in diagnostic, therapeutic, and prophylactic applications.
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