PROBLEM TO BE SOLVED: To provide techniques for promoting migration, to ocular tissue, of a halogenated isoquinoline derivative in a halogenated isoquinoline derivative-containing ophthalmic composition.SOLUTION: An ophthalmic composition contains a compound represented by the general formula (1) in the figure, where X represents a halogen atom, or a salt thereof, or a solvate of them, and a lower aliphatic carboxylic acid.SELECTED DRAWING: NoneCOPYRIGHT: (C)2018,JPO&INPIT【課題】ハロゲン化イソキノリン誘導体含有眼科用組成物において、ハロゲン化イソキノリン誘導体の眼組織への移行を促進させる技術の提供。【解決手段】次の一般式(1)[式中、Xはハロゲン原子を示す。]で表される化合物若しくはその塩又はそれらの溶媒和物、及び低級脂肪族カルボン酸類を含有する、眼科用組成物。【選択図】なし