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REDUCTION OF FLAKE-LIKE AGGREGATION IN NANOPARTICULATE ACTIVE AGENT COMPOSITIONS
专利权人:
Alkermes Pharma Ireland Limited
发明人:
Niels P. Ryde,Peter Snyder,Wei Liu,David M. Slifer
申请号:
US15130255
公开号:
US20160228554A1
申请日:
2016.04.15
申请国别(地区):
US
年份:
2016
代理人:
摘要:
This invention is directed to reduction of flake-like aggregation in nanoparticulate compositions. Also encompassed by the invention are compositions comprising a nanoparticulate active agent, at least one surface stabilizer and a flake-like aggregation reducing agent, such as a buffer and a sugar. The nanoparticulate active agent compositions comprise particles of the active agent having an effective average particle size of less than about 2000 nm.
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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