An enteral feeding adapter system for use with a bottle cap having a dispensing opening, and an oral syringe having a male syringe element. The system includes a cap adapter having a male adapter element configured to be insertable into the dispensing opening to place the cap adapter in fluid communication with the bottle cap. The cap adapter further includes a male ENFit connector in fluid communication with the male adapter element. The enteral feeding adapter system further includes a syringe adapter having a female ENFit connector configured to be selectively engageable with the male ENFit connector to place the syringe adapter in fluid communication with the cap adapter. The syringe adapter further includes a female adapter element in fluid communication with the female ENFit connector and configured to receive the male syringe element to place the syringe adapter element in fluid communication with the oral syringe.