Bruce Panilaitis;David L. Kaplan;Fiorenzo Omenetto;Eleanor M. Pritchard;Jordan Axelrad
发明人:
David L. Kaplan,Bruce Panilaitis,Eleanor M. Pritchard,Fiorenzo Omenetto,Jordan Axelrad
申请号：
US13254629
公开号：
US20120052124A1
申请日:
2010.03.04
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention provides for silk fibroin-based compositions comprising one or more antibiotic agents for prevention or treatment of microbial contamination, methods of making antibiotic-containing silk scaffold, methods of stabilizing antibiotics in silk scaffolds, and methods for preventing or treating microbial contamination using the antibiotic-containing compositions. Various methods may be used to embed the antibiotic(s) into the silk fibroin-based compositions. The antibiotic-containing compositions of the invention are particular useful for stabilizing antibiotics, preventing bacterial infections, and for medical implants, tissue engineering, drug delivery systems, or other pharmaceutical or medical applications.
