FREISSMUTH MICHAEL,ZEBEDIN-BRANDL EVA -MARIA,BERGMAYR CHRISTIAN,HUSSAN FILZA
申请号：
ZA201304743
公开号：
ZA201304743B
申请日:
2013.06.25
申请国别(地区):
ZA
年份:
2014
代理人:
摘要：
The present invention provides a novel method for enhancing engraftment of haematopoetic stem cells by an ex-vivo pretreatment comprising the steps of obtaining a sample containing haematopoetic stem cells and admixing a prostacyclin analog to obtain a mixture, incubating said mixture for a period of time sufficient to stimulate G alphas-signalling in said cells and optionally and isolating said stimulated cells. Further, a composition comprising a prostacyclin analog for use in the treatment of individuals undergoing haematopoetic stem cell transplantation is provided.
