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METHOD FOR PREVENTION OR TREATMENT OF ONE OR MORE OF DISEASES RELEVANT TO THE PROTEIN IN THE PROTEIN-CELL CONJUGATE, MALIGNANT TUMORS, INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS AND AUTOIMMUNE DISEASES
专利权人:
发明人:
Changqing Xia,Yixian Guo,Haitao Wu,Suigui Wan
申请号:
US16026877
公开号:
US20180311370A1
申请日:
2018.07.03
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention pertains to immunology, biomedicine field, specifically relates to a method for prevention or treatment of one or more of diseases relevant to the protein in the protein-cell conjugate, malignant tumors, infectious diseases caused by pathogenic microorganisms and autoimmune diseases. The method includes a step of administering to a subject in such need a prophylactically or therapeutically effective amount of a protein-cell conjugate, the said protein-cell conjugate is a conjugate formed by covalently linking a protein and a cell to a linker, respectively the cell has free sulfhydryl groups distributed on its surface, when the cell is not linked to the linker the linker is derived from a bifunctional cross-linking agent, and the bifunctional cross-linking agent comprises both a group capable of reacting with an amino group and a group capable of reacting with a sulfhydryl group.
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中国工程科技知识中心
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