WANG, TIANSHENG,GREEN, JEREMY,CORNEBISE, MARK,LEDFORD, BRIAN,PARSONS, JONATHAN,TANNER, ADAM,WESTCOTT, JAMES
申请号：
NZ57534607
公开号：
NZ575346A
申请日:
2007.09.04
申请国别(地区):
NZ
年份:
2012
代理人:
摘要：
Disclosed is a furan substituted thiazole of formula (I) where the substituents are as disclosed in the specification. Examples of compounds of formula (I) include: (R)-5-(2-acetamido-4-methylthiazol-5-yl)-N-(2-hydroxy-1-phenylethyl)furan-2-carboxamide and EthyI 5-(2-(cyclopropanecarboxamido)-4-methylthiazol-5-yl)furan-2-carboxylate. Also disclosed is a pharmaceutical composition comprising a compound of formula (I) and the use of a compound of formula (I) in the manufacture of a medicament for treating or lessening the severity of a disease or condition selected from rheumatoid arthritis, systemic lupus erythematosus, atherosclerosis, lacrimal parotid gland syndrome, chronic obstructive pulmonary disease, pancreatitis, myocardial infarction, diabetes, multiple sclerosis or cancer.
