DICER SUBSTRATE AGENTS AND METHODS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION
- 专利权人:
- DICERNA PHARMACEUTICALS; INC.
- 发明人:
- BROWN, BOB, DALE
- 申请号:
- EP10838037
- 公开号:
- EP2513334A4
- 申请日:
- 2010.06.25
- 申请国别(地区):
- EP
- 年份:
- 2014
- 代理人:
- 摘要:
- This invention relates to compounds, compositions, and methods useful for reducing KRAS target RNA and protein levels via use of Dicer substrate siRNA (DsiRNA) agents possessing asymmetric end structures.
- 来源网站:
- 中国工程科技知识中心
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- 비대칭 이중가닥 RNA에 의한 KRAS의 특이적 저해를 위한 방법 및 조성물
- COMPOSITIONS AND METHODS OF INHIBITING GENE EXPRESSION IN A LUNG
- COMPOSITIONS AND METHODS OF INHIBITING GENE EXPRESSION IN A LUNG
- Interfering nucleic acids, inhibiting the expression of target genes in insect species, coding of isolated polynucleic acids, DNA structure, Clula Hugheside, consisting of interfering nucleic acids, and methods for reducing objective gene expression Insect pests.
- 엔도siRNA 에 의한 대사 항상성, 외부 스트레스 저항성 또는 수명 조절 방법