A receptacle for breast milk extraction using an external vacuum source and method of extraction are disclosed. The receptacle may include an open end for receiving a breast and a vacuum transfer zone on an outer surface thereof. The vacuum transfer zone may have a surface area of at least 1 cm2 and the vacuum transfer area may be in pressure communication with an interior of the receptacle and the external vacuum source. A deformable diaphragm may block fluid communication between said interior of the receptacle and said external vacuum source. The diaphragm may limit a volume change associated pressure fluctuations. The receptacle and/or the diaphragm may be single use. Milk may optionally be collected into a flexible single use collection and/or storage vessel.
