Suneel K. RASTOGI,Niranjan RAO,Antonia PERICLOU,Wattanaporn ABRAMOWITZ,Mahendra G. DEDHIYA,Shashank MAHASHABDE
申请号：
US14228944
公开号：
US20140213659A1
申请日:
2014.03.28
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention provides pharmaceutical compositions given once daily containing at least one therapeutically active ingredient selected from the group consisting of memantine and a pharmaceutically acceptable salt of memantine, and a pharmaceutically acceptable polymeric matrix carrier. The dosage forms of the invention sustain the release of the therapeutically active agent from about 4 to about 24 hours when said dosage form is exposed to aqueous solutions. following entry of said form into a use environment, wherein said dosage form has a dissolution rate of more than about 80% after passage of about 6 hours to about 12 hours following said entry into said use environment.
