Methods of treating cancer with low density lipoprotein-related protein 6 (LRP6)—；half life extender constructs

• 收藏
• 分享

专利权人:

Novartis AG

发明人:

David Jenkins,Ming Lei,Andreas Loew,Li Zhou

申请号：

US15802250

公开号：

USRE047860E1

申请日:

2017.11.02

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The present invention relates to LRP6 constructs that bind to LRP6 receptor. The LRP6 constructs comprise at least one LRP6 binding moiety and a half-life extender molecule such that the LRP6 construct inhibit the Wnt signaling pathway without potentiation of the Wnt signal. The LRP6 constructs also have an increased half-life to provide more time for the therapeutic benefit.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/