Extrasynapticx(336 1250 0 Compound 9 1000 Diazepam '47; 750 4- , 0 500 2 0 0.01 Concentration (PM) FIG. 1A W O 20 17 / 15 6 103 Al 1 0 (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date WO 2017/156103 Al 14 September 2017 (14.09.2017) WIPO I PCT (51) International Patent Classification: (72) Inventor; and A61K 31/57 (2006.01) A61K 31/575 (2006.01) (71) Applicant : COLQUHOUN, Helen [US/US]; 23 Regis A61K 31/56 (2006.01) A61K 31/58 (2006.01) Road, Arlington, MA 02474 (US). 111111111111110111011111111111010111110 0111111111111101011111011111111111110111111 (21) International Application Number: PCT/US2017/021325 (22) International Filing Date: 8 March 2017 (08.03.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/305,279 8 March 2016 (08.03.2016) US 62/355,174 27 June 2016 (27.06.2016) US 62/355,669
