ADVAXIS, INS.;NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMANS SERVICES (DHHS), U.S. GOVERNMEN
发明人:
Robert Petit,Anu Wallecha,Zhisong Chen,Jay A Berzofsky,Samir Khleif
申请号：
US15123468
公开号：
US20170080064A1
申请日:
2015.03.05
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention is directed to methods for increasing T-cell effector cell to regulatory T cell ratio. The invention is further directed to methods of treating, protecting against, and inducing an immune response against a tumor, comprising the step of administering to a subject a recombinant Listeria strain, comprising a fusion peptide that comprises an LLO fragment and tumor-associated antigen.
