An infusion set (10, 200) preferably for use with an inserter is disclosed.Theinfusion set (10, 200) includes a septum cap (70, 210) that encapsulates anupper resilientseptum (80) and a lower resilient septum (90) of a base (40), and includes atleast oneradial port (130, 230) to receive insertion of a blunt cannula (110) when anextension sethub (30, 180) is engaged with the infusion set (10, 200) in a directionsubstantially parallelto the skin surface. The extension set hub (30, 180) is configured to providea snap-fitengagement with the septum cap (70, 210), wherein the blunt cannula (110) oftheextension set hub (30, 180) is guided through the radial port (130, 230) ofthe septum cap(70, 210) and penetrates the interface between the upper septum (80) and thelower septum(90). The extension set hub (30, 180) and the septum cap (70, 210) can berotated in a 360degree manner about the base (40) of the infusion set.