РОБИНСОН Майкл Р. (US),БЁРК Джеймс (US),ШИФФМАН Ретт (US)
申请号：
RU2012133880/15
公开号：
RU2012133880A
申请日:
2011.01.21
申请国别(地区):
RU
年份:
2014
代理人:
摘要：
1. A method for treating ocular diseases, comprising the following steps: providing at least two biodegradable sustained-release implants containing at least one therapeutic agent； implanting at least two biodegradable prolonged-release implants into the anterior chamber eyes； curing eye disease, wherein at least two biodegradable sustained release implants release about 100 ng per day of at least one bioactive agent for a period of more than about 1 month. The method according to claim 1, characterized in that the eye disease is glaucoma. The method according to claim 1, characterized in that the eye disease is increased intraocular pressure. The method according to claim 1, characterized in that the extended-release implant releases approximately 70% of at least one therapeutic agent in the first month. The method according to claim 1, characterized in that at least one therapeutic agent is selected from the group consisting of latanoprost, bimatoprost and travoprost, as well as their salts, esters and inactive forms of drugs. The method according to claim 1, characterized in that at least two biodegradable sustained release implants contain approximately 30% of the therapeutic agent. The method according to claim 1, characterized in that at least two biodegradable sustained release implants contain from about 5 to about 70% poly (D, L-lactide). The method according to claim 1, characterized in that at least two biodegradable implants with prolonged1. Способ лечения глазных заболеваний, включающий следующие этапы:обеспечение, по меньшей мере, двумя биоразлагаемыми имплантатами с пролонгированным высвобождением, содержащими, по меньшей мере, один терапевтический агент；имплантацию, по меньшей мере, двух биоразлагаемых имплантатов с пролонгированным высвобождением, в переднюю камеру глаза； илечение заболевания глаз,при этом, по меньшей мере, два биоразлагаемых имплантата с пролонгированным высвобождением высвобождают приблизительно 100 нг в день, по меньшей мере, одн
