A patient interface for use in delivering a flow of breathable gas to an airway of a patient includes a first seal adapted to contact the patients face and seal a first space between the patient interface and the patients face at a first positive pressure and a second seal adapted to contact the patients face and seal a second space between the patient interface and the patients face at a second positive pressure. The first seal also seals the first space from the second space. A leak reducing element may be provided on a seal to reduce and/or diffuse leakage of gas. A vacuum line configured to create a negative pressure may be provided in the second space to remove any gas leaking from the first space to the second space. A seal may be connected to a conduit for delivering the flow of gas that is incorporated into a frame of the patient interface. The seal may be inflatable by the flow of breathable gas to pressurize the seal against the patients face and include a vent that directs the flow of breathable gas to a space between the patient interface and the patients face. A cuff may be provided over the seal in the nasal bridge region to direct any leakage of the gas flow from the seal in the nasal bridge region in a direction away from the patients eyes.
