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AMIDES DE PYRIDONE DEUTERES ET LEURS PROMEDICAMENTS UTILISES EN TANT QUE MODULATEURS DE CANAUX SODIQUES
专利权人:
VERTEX PHARMACEUTICALS INCORPORATED
发明人:
JIANG, LICONG,HADIDA RUAH, SARA SABINA
申请号:
CA3063901
公开号:
CA3063901A1
申请日:
2018.05.16
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. The compounds have the formula (I) wherein R is H or CH2OPO(OH)2. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
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