作為鈣感測受體調節劑之取代二氫苯並哌喃化合物农业专利-农业学术服务平台

发明人:: SHUKLA, MANOJKUMAR RAMPRASAD,苏克拉　曼诺库马尔　拉姆普拉,蘇克拉　曼諾庫馬爾　拉姆普拉,SARDE, ANKUSH GANGARAM,沙德　安库许　冈格朗,沙德　安庫許　岡格朗,LORIYA, RAJESHKUMAR MAGANLAL,罗利亚　瑞杰许库马尔　马詹拉,羅利亞　瑞傑許庫馬爾　馬詹拉,PACHPUTE, VIPUL DILIP,佩屈普特　凡保　德利普,佩屈普,苏克拉曼诺库马尔拉姆普拉,蘇克拉曼諾庫馬爾拉姆普拉,沙德安库许冈格朗,沙德安庫許岡格朗,罗利亚瑞杰许库马尔马詹拉,羅利亞瑞傑許庫馬爾馬詹拉,佩屈普特凡保德利普

摘要：: The present invention provides calcium sensing receptor modulators (CaSR). In particular, the compounds described herein are useful for treating, managing, and/or liessening the severit of diseases, disorders, syndromes and/or condtions associated wih the modulation of calcium sensing receptors (CaSR). The invention also provides herein the pharmaceutical compositions thereof, and methods for treating, managing, and/or lessening the severityof diseases, disorders, syndromes and/or conditions associated with the modulation of CaSR. The invention also relates to process for the preparation of the compounds of the invention.發明係提供鈣感測受體調節劑(CaSR)。特別地，本文所描述之化合物對於治療、管理及/或減輕與鈣感測受體(CaSR)調節相關聯的疾病、失調、綜合症或症狀嚴重性是有用的。本發明亦於本文提供其藥學組成物，以及治療、管理及/或減輕與CaSR調節相關聯的疾病、失調、綜合症或症狀嚴重性的方法。本發明亦相關於本發明之化合物的製備方法。