LANE, Rodney James,HUCKSON, Matthew James,KYUNG, Chris,LANE, David Michael,KHIN, Nyan Ye,MURPHY, Scott Ryan
申请号:
EP17851976
公开号:
EP3515520A4
申请日:
2017.03.24
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
A method of delivering a therapeutic substance for treatment to a region of the body through vascular isolation and manipulation of fluid flux into and from the region of the body including the steps of: restricting vascular inflow to the region of the body; washing out oncotically active plasma proteins from the region of the body by increasing the outward oncotic pressure gradient from the region of the body; inducing ischemia in the region of the body; controlling the pressure and fluid flow of the main blood vessels to and from the region of the body; providing the therapeutic substance to the region of the body when the fluid flow to the region of the body is controlled.