The Brigham and Women's Hospital, Inc.;Massachusetts Institute of Technology
发明人:
Maria Jose M. N. Pereira,Woo-Kyung Cho,Robert S. Langer,Jeffrey M. Karp
申请号：
US14092015
公开号：
US20140148846A1
申请日:
2013.11.27
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Adhesive articles containing microtopography, such as microprotrusions, and a coating of adhesive glue, such an adhesive having known toxicity and/or tissue reactive functional groups are described herein. The articles described herein contain a substrate, a plurality of microfeatures, and an adhesive, such as an adhesive glue. The articles described herein exhibit a 90° pull off adhesion of at least about 1.5 N/cm2. The articles described herein can contain less adhesive than when the adhesive is used alone without microtopography and yet exhibit equivalent adhesive strength with little or no toxicity or other adverse side effects (e.g., exothermic reaction).
