ANALOGUES DE N-(3-(PYRIMIDIN-4-YL)PHÉNYL) SUBSTITUÉ UTILISÉS EN TANT QU'INHIBITEURS DE RÉCEPTEUR TYROSINE KINASE BTK

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专利权人:

UNIVERSITY OF UTAH RESEARCH FOUNDATION

发明人:

VANKAYALAPATI, HARIPRASAD,SORNA, VENKATASWAMY,WARNER, STEVEN, L.,BEARSS, DAVID, J.,SHARMA, SUNIL

申请号：

EP13844466

公开号：

EP2903972A4

申请日:

2013.10.04

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

In one aspect, the invention relates to substituted N-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of the BTK kinase； synthetic methods for making the compounds； pharmaceutical compositions comprising the compounds； and methods of using the compounds and compositions to treat disorders associated with dysfunction of the BTK kinase. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

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