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Pharmaceutical compositions of selective factor Xa inhibitors for oral administration
专利权人:
Thomas W. Leonard
发明人:
Thomas W. Leonard,David C. Coughlan,Alan Cullen
申请号:
US13073202
公开号:
US09089484B2
申请日:
2011.03.28
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention provides pharmaceutical compositions for oral administration comprising a therapeutically effective amount of a selective factor Xa inhibitor or a pharmaceutically acceptable salt thereof and an enhancer, wherein the enhancer is a medium chain fatty acid or a salt, ester, ether, or derivative of a medium chain fatty acid and has a carbon chain length of from about 4 to about 20 carbon atoms. The present invention also provides a method for obtaining a reproducible bioavailability of selective factor Xa inhibitor in an object after oral administration comprising orally administering a pharmaceutical composition as described above.
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中国工程科技知识中心
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http://www.ckcest.cn/home/
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