MACARY, Paul Anthony,TEOH, Ee Ping Evelyn,HANSON, Brendon John,TEO, En Wei,LIM, Angeline Pei Chiew,NG, Mah Lee Mary,LOK, Shee Mei,KUKKARO, Petra Eveliina
申请号:
ES11848839
公开号:
ES2644236T3
申请日:
2011.12.14
申请国别(地区):
ES
年份:
2017
代理人:
摘要:
Compositions and methods for the treatment or prevention of Dengue virus infection in a vertebrate subject are provided. In particular, human neutralizing monoclonal antibodies to Dengue virus isolated from EBV immortalized B cells derived from patients who have recovered from Dengue infection are disclosed. Methods are provided for administering such antibodies to a vertebrate subject in an amount effective to reduce, eliminate, or prevent relapse from infection.