Hai-Yun XIAO,T. G. Murali DHAR,Ning LI,Jingwu DUAN,Bin JIANG,Zhonghui LU,Khehyong NGU,William J. PITTS,Joseph TINO
申请号：
HK18111924
公开号：
HK1252623A1
申请日:
2018.09.17
申请国别(地区):
HK
年份:
2019
代理人:
摘要：
Disclosed are compounds of Formula (I) or a salt thereof, wherein: A is CR1 or N； B is CR3 or N； D is CR4 or N； L1 is -(CR7R7)m-； L2 is -(CR7R7)n-； and X, Z, R1, R2, R3, R4, R5,and R6 are define herein. Also disclosed are methods of using such compounds as modulators of TNFα, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.
