Magundappa Ravi L. Hadimani,Shalabh Gupta,Shane Harstad,Vitalij Pecharsky,David C. Jiles
申请号:
US15332940
公开号:
US20170119909A1
申请日:
2016.10.24
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A particle usable as T1 and T2 contrast agents is provided. The particle is a gadolinium silicide (Gd5Si4) particle that is ferromagnetic at temperatures up to 290 K and is less than 2 μm in diameter. An MRI contrast agent that includes a plurality of gadolinium silicide (Gd5Si4) particles that are less than 1 μm in diameter is also provided. A method for creating gadolinium silicide (Gd5Si4) particles is also provided. The method includes the steps of providing a Gd5Si4 bulk alloy grinding the Gd5Si4 bulk alloy into a powder and milling the Gd5Si4 bulk alloy powder for a time of approximately 20 minutes or less.