COMPOSITIONS AND METHODS FOR EFFECTING THE LEVELS OF HIGH DENSITY LIPOPROTEIN (HDL) CHOLESTEROL AND APOLIPOPROTEIN AI, VERY LOW DENSITY LIPOPROTEIN (VLDL) CHOLESTEROL AND LOW DENSITY LIPOPROTEIN (LDL) CHOLESTEROL
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;AVENTIS PHARMACEUTICALS PRODUCTS INC.
发明人:
JAYE, MICHAEL,LYNCH, KEVIN J.,AMIN, DILIP V.,DOAN, KIM-ANH THI,MARCHADIER, DAWN,MAUGEAIS, CYRILLE,RADER, DANIEL J.,KRAWIEC, JOHN A.,SOUTH, VICTORIA J.
申请号：
CA2363486
公开号：
CA2363486C
申请日:
2000.03.24
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
Compositions and methods for raising the level of HDL cholesterol andapolipoprotein AI in a patient and for lowering the levels of VLDL cholesteroland LDL cholesterol in a patient, including compositions and methods whicheffect the expression of a gene, LIPG, which encodes a lipase enzyme that is amember of the tryacylglycerol lipase family or which effect the enzymaticactivity of the enzyme.
