Solid forms of (R)-1(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3- dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide

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专利权人:

Vertex Pharmaceuticals Incorporated

发明人:

Keshavarz-Shokri, Ali,Zhang, Beili,Alcacio, Tim Edward,Lee, Elaine Chungmin,Zhang, Yuegang,Krawiec, Mariusz

申请号：

AU2016208341

公开号：

AU2016208341B2

申请日:

2016.07.27

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

#$%^&*AU2016208341B220180524.pdf#####ABSTRACT The present invention relates to solid state forms, for example, crystalline and amorphous forms, of (R)-1-(2,2-difluorobenzo[ d] [ 1,3 ]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide, pharmaceutical compositions thereof, and methods therewith.

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