Peter G. Schultz;Yongqin Wan;John Tellew;Michael Cooke;Shifeng Pan;Xing Wang;Anthony E. Boitano
发明人:
Anthony E. Boitano,Michael Cooke,Shifeng Pan,Peter G. Schultz,John Tellew,Yongqin Wan,Xing Wang
申请号:
US13857939
公开号:
US09580426B2
申请日:
2013.04.05
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to compounds and compositions for expanding the number of CD34+ cells for transplantation. The invention further relates to a cell population comprising expanded hematopoietic stem cells (HSCs) and its use in autologous or allogeneic transplantation for the treatment of patients with inherited immunodeficient and autoimmune diseases and diverse hematopoietic disorders to reconstitute the hematopoietic cell lineages and immune system defense.