Ali Hussain,Linda Cahalan,Greg Johnson,Mark Gartner,Patrick Cahalan,Brian J Fill,Jeffrey W. Speakman
申请号：
US14214248
公开号：
US09693841B2
申请日:
2014.03.14
申请国别(地区):
US
年份:
2017
代理人:
摘要：
A variety of medical devices including staples sutures and dental floss with surface treatment on at least one tissue-facing surface to improve biologic function such as to control tissue adhesion are disclosed including heparin surface treatment which provides heparin present in an amount to yield heparin bioactivity of at least one of i) an ATIII binding of at least 2 pmol/cm2, and ii) a thrombin deactivation of at least 0.2 IU/cm2 an acrylic surface treatment for coupling thereto of a heparin surface treatment, a collagen surface treatment or both and an amino-functional polysiloxane surface treatment for coupling thereto of a heparin surface treatment.
