YAGODICH MARY K,CITRON MICHAEL P,DISTEFANO DANIEL J,KRAH DAVID L,LIANG XIAOPING
申请号:
ZA201103259
公开号:
ZA201103259B
申请日:
2011.05.05
申请国别(地区):
ZA
年份:
2012
代理人:
摘要:
The present invention features live, attenuated respiratory syncytial viruses (RSV) useful as vaccines against RSV infection and/or the development of severe RSV-associated illnesses. The disclosed viruses are attenuated to the extent of being nonpathogenic when administered to a subject but substantially retain the antigenic and immunogenic properties of wild-type RSV.