Caius G. Radu,Hsiang-I Liao,Nagichettiar Satyamurthy,Johannes Czernin,Jennifer M. Murphy,David A. Nathanson
申请号:
US14002964
公开号:
US09688673B2
申请日:
2012.03.08
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention provides compounds that bind to deoxycytidine kinase (dCK) and compositions including pharmaceutically acceptable compositions containing the compounds. The compounds are useful in treating diseases and disorders where dCK activity is implicated such as cancer and immune disorders. The compounds also find use in clinical methodologies including positron emission tomography (PET) imaging.