QUN DANG,JORGE E. GOMEZ-GALENO,RAJA K. REDDY,PAUL VAN POELJE,ROBERT HUERTA LEMUS,THANH HUU NGUYEN,MATTHEW P. GROTE,SCOTT J. HECKER,VENKAT REDDY MALI,MINGWEI CHEN,ZHILI SUN,SERGE HENRI BOYER,HAIQING LI
申请号:
PT08729528
公开号:
PT2129654E
申请日:
2008.02.11
申请国别(地区):
PT
年份:
2014
代理人:
摘要:
The present invention provides for novel compounds of Formula I and pharmaceutically acceptable salts and co-crystals thereof which have glucagon receptor antagonist or inverse agonist activity. The present invention further provides for pharmaceutical compositions comprising the same as well as their use in methods of treating, preventing, delaying the time to onset or reducing the risk for the development or progression of a disease or condition for which one or more glucagon receptor antagonist is indicated, including Type I and II diabetes, insulin resistence and hyperglycemia.