ACTIVIN-ACTRIIA ANTAGONISTS AND USES FOR PROMOTING BONE GROWTH

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专利权人:

ACCELERON PHARMA INC

发明人:

KNOPF, JOHN,SEEHRA, JASBIR

申请号：

IN2553DEN2015

公开号：

IN2553DEN2015A

申请日:

2015.03.27

申请国别(地区):

IN

年份:

2015

代理人:

摘要：

In certain aspects, the present invention provides compositions and methods for promoting bone growth and increasing bone density. The invention disclose polypeptide comprising an amino acid sequence that is at least 90% identical to the amino acid sequence of SEQ ID NO:7, wherein the N-terminus of the polypeptide is ILGRSETQE. The invention discloses methods of making ActRIIA polypeptide and pharmaceutical preparation

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